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Symbol
Name
ID
Trp53
transformation related protein 53
MGI:98834
Phenotype annotations related to limbs/digits/tail
Darker colors indicate more annotations
Human Phenotypes
Abnormal femoral metaphysis morphology
Abnormal tibial metaphysis morphology
Abnormal metaphysis morphology
Disease(s) Associated with TP53
osteosarcoma

Mouse Phenotypes
abnormal digit pigmentation
increased foot pad pigmentation
increased tail pigmentation
abnormal limb morphology
decreased bone mineral density of humerus
short humerus
abnormal tibia morphology
abnormal tail tip morphology
kinked tail
Availability Mouse Genotype
Trp53tm1.1Manf/Trp53tm1.1Manf
Trp53tm1.1Tldo/Trp53tm1.1Tldo
Trp53tm1.1Tldo/Trp53+
Trp53tm1Att/Trp53+
Tg(KRT5-cre)5132Jlj/0  (conditional)
Tg(CMV-cre)1Cgn/0
Trp53tm4Att/Trp53+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory