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Symbol
Name
ID
Tpm1
tropomyosin 1, alpha
MGI:98809
Phenotype annotations related to mortality/aging
Darker colors indicate more annotations
Human Phenotypes
Sudden cardiac death
Disease(s) Associated with TPM1
hypertrophic cardiomyopathy 3

Mouse Phenotypes
premature death
embryonic lethality during organogenesis, complete penetrance
embryonic lethality between implantation and placentation, complete penetrance
embryonic lethality, complete penetrance
Availability Mouse Genotype
Tpm1tm1Dfw/Tpm1tm1Dfw
Tpm1tm1Jse/Tpm1tm1Jse
Tpm1em1Clo/Tpm1+
Tg(Myh6-Tpm1*E54K)30Dfw/0
Tg(Myh6-Tpm1*E54K)67Dfw/0
Tg(Myh6-Tpm1*E180G)57Dfw/0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory