Symbol
Name
ID

Thra
thyroid hormone receptor alpha
MGI:98742

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hoarse voice
Disease(s) Associated with THRA	Hoarse voice
congenital nongoitrous hypothyroidism 6

Mouse Phenotypes

behavior/neurological phenotype

abnormal contextual conditioning behavior

abnormal object recognition memory

decreased exploration in new environment

decreased food intake

increased anxiety-related response

decreased startle reflex

increased startle reflex

limb grasping

ataxia

decreased grip strength

abnormal locomotor coordination

increased vertical activity

hyperactivity

abnormal pup retrieval

Availability

Mouse Genotype

Thra^tm1.1Fcas/Thra^tm1.1Fcas

Thra^tm1Ven/Thra^tm1Ven

Thra^tm2Ven/Thra^tm2Ven

Thra^{tm1b(EUCOMM)Wtsi}/Thra⁺

Thra^tm1Brnt/Thra⁺

Thra^tm3Ven/Thra⁺

Thra^tm1Ffla/Thra⁺
Tg(Sycp1-cre)4Min/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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