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Symbol
Name
ID
Thbd
thrombomodulin
MGI:98736
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal leukocyte adhesion
abnormal spleen morphology
increased spleen weight
abnormal leukocyte physiology
increased circulating interleukin-1 beta level
decreased circulating interleukin-6 level
increased circulating interleukin-6 level
decreased circulating tumor necrosis factor level
increased circulating tumor necrosis factor level
abnormal acute phase protein level
decreased tumor necrosis factor secretion
increased susceptibility to endotoxin shock
decreased susceptibility to bacterial infection
decreased susceptibility to bacterial infection induced morbidity/mortality
Availability Mouse Genotype
Thbdtm1Wlr/Thbdtm1Wlr
Thbdtm2.1Emc/Thbdtm2.1Emc
Thbdtm2Emc/Thbdtm2Emc
Thbdtm1Wlr/Thbdtm2Rdr
Thbdtm1.1Hlwu/Thbdtm1.1Hlwu
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)
Tg(Tek-cre)1Ywa/0
Thbdtm2Rdr/Thbdtm2Wlr  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory