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Symbol
Name
ID

Tgfbr2
transforming growth factor, beta receptor II
MGI:98729

Phenotype annotations related to mortality/aging

Darker colors indicate more annotations

Human Phenotypes	Death in early adulthood	Death in infancy
Disease(s) Associated with TGFBR2	Death in early adulthood	Death in infancy
Lynch syndrome

Mouse Phenotypes		premature death	lethality throughout fetal growth and development, complete penetrance	perinatal lethality	neonatal lethality	postnatal lethality, complete penetrance	embryonic lethality during organogenesis, complete penetrance	prenatal lethality, complete penetrance	preweaning lethality, complete penetrance
Availability	Mouse Genotype	premature death		perinatal lethality	neonatal lethality	postnatal lethality, complete penetrance		prenatal lethality, complete penetrance	preweaning lethality, complete penetrance
	Tgfbr2^{em1(IMPC)Rbrc}/Tgfbr2^{em1(IMPC)Rbrc}
	Tgfbr2^tm1.1Hlm/Tgfbr2^tm1.1Hlm
	Tgfbr2^tm1Hlm/Tgfbr2^tm1Hlm
	Tgfbr2^tm1Mmt/Tgfbr2^tm1Mmt
	Tgfbr2^tm1.1Hcd/Tgfbr2⁺
	Tgfbr2^tm1.2Hlm/Tgfbr2^tm1.2Hlm H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)
	Tgfbr2^tm1.2Hlm/Tgfbr2^tm1.2Hlm Twist2^tm1(cre)Dor/Twist2⁺ (conditional)
	Tgfbr2^tm1.2Hlm/Tgfbr2^tm1.2Hlm Tg(KRT14-cre)52Smr/0 (conditional)
	Tgfbr2^tm1.2Hlm/Tgfbr2^tm1.2Hlm Tg(Cd4-cre)1Cwi/0 (conditional)
	Tgfbr2^tm1.2Hlm/Tgfbr2^tm1.2Hlm A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺ (conditional)
	Tgfbr2^tm1Karl/Tgfbr2^tm1Karl Tg(Mx1-cre)1Cgn/0 (conditional)
	Tgfbr2^tm1Karl/Tgfbr2^tm1Karl Tg(Tie1-cre)9Ref/0 (conditional)
	Tgfbr2^tm1Karl/Tgfbr2^tm1Karl H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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