|
Symbol Name ID |
Tgfbr2
transforming growth factor, beta receptor II MGI:98729 |
| Darker colors indicate more annotations |
| Human Phenotypes | Craniosynostosis |
Dolichocephaly |
Micrognathia |
Retrognathia |
Malar flattening |
Long face |
Narrow face |
Adenoma sebaceum |
Bifid uvula |
Cleft palate |
High palate |
Narrow palate |
Salivary gland neoplasm |
Dental crowding |
Downslanted palpebral fissures |
| Disease(s) Associated with TGFBR2 | |||||||||||||||
| Loeys-Dietz syndrome 2 | |||||||||||||||
| Lynch syndrome | |||||||||||||||
| Marfan syndrome |
| Mouse Phenotypes | abnormal fourth pharyngeal arch artery morphology |
abnormal craniofacial bone morphology |
abnormal cranium morphology |
small cranium |
abnormal neurocranium morphology |
absent frontal bone |
abnormal parietal bone morphology |
abnormal molar morphology |
abnormal enamel mineralization |
abnormal enamel morphology |
reduced enamel thickness |
abnormal tooth attrition |
abnormal mandible morphology |
absent mandibular angle |
small mandibular condyloid process |
small mandibular coronoid process |
small mandible |
small maxilla |
abnormal palate development |
abnormal palatal mesenchymal cell proliferation |
abnormal primary palate development |
abnormal palatal shelf morphology |
abnormal palatal shelf fusion at midline |
palatal shelves fail to meet at midline |
palatal shelf hypoplasia |
abnormal palate morphology |
abnormal hard palate morphology |
abnormal soft palate morphology |
abnormal soft palate muscle morphology |
small levator veli palatini muscle |
small tensor veli palatini muscle |
cleft soft palate |
cleft secondary palate |
abnormal nasal septum morphology |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||
| Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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| Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm Tg(KRT14-cre)52Smr/0 (conditional) |
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| Tgfbr2tm1Karl/Tgfbr2tm1Karl H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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| Tgfbr2tm1Karl/Tgfbr2tm1Karl Tg(AMELX-cre)A1Kul/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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