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Symbol
Name
ID
Tcf4
transcription factor 4
MGI:98506
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Esophagitis
Keratitis
Disease(s) Associated with TCF4
Fuchs' endothelial dystrophy
Pitt-Hopkins syndrome

Mouse Phenotypes
immune system phenotype
decreased thymocyte number
abnormal B cell differentiation
decreased pro-B cell number
abnormal T cell differentiation
increased double-negative T cell number
decreased double-positive T cell number
spleen hypoplasia
abnormal T cell physiology
Availability Mouse Genotype
Tcf4tm1.1Hmb/Tcf4tm1.1Hmb *
Tcf4tm1Zhu/Tcf4tm1Zhu
Tcf4tm1.1Hmb/Tcf4+
Tcf4tm1Hmb/Tcf4tm1Zhu
Tg(Kit-cre)143Hmb/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/04/2019
MGI 6.14
The Jackson Laboratory