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Symbol Name ID |
Tbx1
T-box 1 MGI:98493 |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Splenomegaly |
Femoral hernia |
Inguinal hernia |
Umbilical hernia |
Short stature |
Obesity |
| Disease(s) Associated with TBX1 | ||||||
| DiGeorge syndrome | ||||||
| hypoparathyroidism | ||||||
| velocardiofacial syndrome |
| Mouse Phenotypes | abnormal upper incisor morphology |
absent upper incisors |
abnormal palate development |
abnormal palatal mesenchymal cell proliferation |
abnormal secondary palate development |
abnormal palatal shelf fusion at midline |
palatal shelves fail to meet at midline |
abnormal palatal shelf size |
decreased palatal shelf size |
increased palatal shelf size |
abnormal facial morphology |
absent masseter muscle |
absent pterygoid muscle |
absent facial muscle |
abnormal palate morphology |
cleft secondary palate |
cleft palate |
abnormal outer ear morphology |
ear lobe hypoplasia |
lowered ear position |
abnormal ear shape |
abnormal external auditory canal morphology |
absent outer ear |
anotia |
small ears |
embryonic growth retardation |
decreased embryo size |
abnormal laryngeal muscle morphology |
short neck |
postnatal growth retardation |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||
| Tbx1em1(IMPC)Mbp/Tbx1em1(IMPC)Mbp | |||||||||||||||||||||||||||||||
| Tbx1m1H/Tbx1m1H | |||||||||||||||||||||||||||||||
| Tbx1m1Jlk/Tbx1m1Jlk | |||||||||||||||||||||||||||||||
| Tbx1tm1.1Dsr/Tbx1tm1.1Dsr | |||||||||||||||||||||||||||||||
| Tbx1tm1Bem/Tbx1tm1Bem | |||||||||||||||||||||||||||||||
| Tbx1tm1Bld/Tbx1tm1Bld | ! | ! | |||||||||||||||||||||||||||||
| Tbx1tm1Dsr/Tbx1tm1Dsr | |||||||||||||||||||||||||||||||
| Tbx1tm1Pa/Tbx1tm1Pa | |||||||||||||||||||||||||||||||
| Tbx1tm2.2Bem/Tbx1tm2.2Bem | |||||||||||||||||||||||||||||||
| Tbx1m1Jlk/Tbx1tm1Bld | |||||||||||||||||||||||||||||||
| Tbx1tm1Bld/Tbx1+ | |||||||||||||||||||||||||||||||
| Tbx1tm1Bld/Tbx1tm5Bld | |||||||||||||||||||||||||||||||
| Tbx1tm2.1Bem/Tbx1tm2.2Bem Foxg1tm1(cre)Skm/Foxg1+ (conditional) |
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| Mesp1tm2(cre)Ysa/Mesp1+ Tbx1tm1Bld/Tbx1tm3Bld (conditional) |
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| Tbx1tm1Bld/Tbx1tm2.1Bem Tfap2atm1(cre)Moon/Tfap2a+ (conditional) |
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| Tbx1tm1Bld/Tbx1tm3Bld Tg(Tek-cre)1Ywa/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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