About   Help   FAQ
Symbol
Name
ID 		Sox9
SRY (sex determining region Y)-box 9
MGI:98371
Phenotype annotations related to craniofacial
Darker colors indicate more annotations
Human Phenotypes
Frontal bossing
Micrognathia
Macrocephaly
Relative macrocephaly
Wide anterior fontanel
Flat face
Small face
Midface retrusion
High forehead
Long philtrum
Submucous cleft hard palate
Cleft palate
High palate
Narrow mouth
Irregular dentition
Carious teeth
Depressed nasal ridge
Depressed nasal bridge
Recurrent upper respiratory tract infections
Abnormality of the sense of smell
Blepharophimosis
Short palpebral fissure
Epicanthus
Disease(s) Associated with SOX9
campomelic dysplasia

Mouse Phenotypes
abnormal craniofacial morphology
abnormal craniofacial bone morphology
abnormal cranium morphology
absent basisphenoid bone
absent styloid process
abnormal Meckel's cartilage morphology
absent Meckel's cartilage
decreased cranium length
absent presphenoid bone
abnormal hyoid bone morphology
absent hyoid bone body
absent hyoid bone lesser horns
small mandible
short mandible
short maxilla
micrognathia
domed cranium
absent incus
absent malleus
absent stapes
abnormal craniofacial development
absent nasal capsule
cleft secondary palate
bilateral cleft palate
bifurcated tongue
short snout
abnormal head shape
shortened head
Availability Mouse Genotype
Sox9Bbfc/Sox9+
Sox9tm1.1Gsr/Sox9+
Sox9tm1Crm/Sox9+
Sox9tm2Crm/Sox9tm2Crm
Tg(Col2a1-cre)1Bhr/0  (conditional)
Sox9tm2Crm/Sox9tm2Crm
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Sox9tm2Crm/Sox9+
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory