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SOS Ras/Rac guanine nucleotide exchange factor 1
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations

Mouse Phenotypes
cardiovascular system phenotype
abnormal cardiovascular system morphology
abnormal blood vessel morphology
vasculature congestion
abnormal myocardial fiber morphology
enlarged myocardial fiber
myocardial fiber degeneration
abnormal myocardial trabeculae morphology
heart left ventricle hypertrophy
heart right ventricle hypertrophy
abnormal heart morphology
abnormal heart atrium morphology
ostium secundum atrial septal defect
abnormal heart position or orientation
thick interventricular septum
ventricular septal defect
enlarged heart
thick aortic valve cusps
aortic valve stenosis
abnormal heart ventricle morphology
abnormal heart left ventricle morphology
distended pericardium
enlarged pericardium
pericardial effusion
cardiac fibrosis
cardiac interstitial fibrosis
abnormal cardiovascular system physiology
abnormal fetal cardiomyocyte proliferation
increased cardiomyocyte apoptosis
Availability Mouse Genotype
Sos1tm1Dlb/Sos1tm1Dlb !
Sos1tm1.2Rak/Sos1+ *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory