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Symbol
Name
ID
Snap25
synaptosomal-associated protein 25
MGI:98331
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Difficulty walking
Easy fatigability
Ataxia
Dysarthria
Poor speech
Areflexia
Global developmental delay
Disease(s) Associated with SNAP25
congenital myasthenic syndrome 18

Mouse Phenotypes
seizures
convulsive seizures
myoclonus
abnormal serotonin level
abnormal brain morphology
abnormal hippocampus CA3 region morphology
abnormal cerebral cortex morphology
abnormal CNS synaptic transmission
abnormal miniature excitatory postsynaptic currents
decreased prepulse inhibition
abnormal PNS synaptic transmission
abnormal endplate potential
decreased synaptic glutamate release
decreased paired-pulse facilitation
enhanced paired-pulse facilitation
Availability Mouse Genotype
Snap25tm1.1Bark/Snap25tm1.1Bark
Snap25tm1Bark/Snap25tm1Bark
Snap25tm1Mcw/Snap25tm1Mcw
Snap25tm1Mtaka/Snap25tm1Mtaka
Snap25tm2Mcw/Snap25tm2Mcw
Snap25Bdr/Snap25+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory