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Symbol
Name
ID
Shh
sonic hedgehog
MGI:98297
Phenotype annotations related to cellular
Darker colors indicate more annotations
Human Phenotypes
Abnormality of chromosome segregation
Disease(s) Associated with SHH
solitary median maxillary central incisor

Mouse Phenotypes
abnormal cell physiology
abnormal neural crest cell apoptosis
increased apoptosis
abnormal neural crest cell migration
abnormal cell proliferation
decreased keratinocyte proliferation
Availability Mouse Genotype
Shhtm1Amc/Shhtm1Amc
Shhtm1Chg/Shhtm1Chg
Shhtm3(cre)Chg/Shhtm3(cre)Chg
Tg(Shh)#Dje/0
Shhtm1Chg/Shhtm2Amc
Nkx2-5tm1(cre)Rjs/Nkx2-5+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory