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Symbol
Name
ID
Spi1
Spi-1 proto-oncogene
MGI:98282
Phenotype annotations related to cellular
Darker colors indicate more annotations
Human Phenotypes
Decreased circulating IgA level
Decreased circulating IgG level
Decreased circulating total IgM
Agammaglobulinemia
Disease(s) Associated with SPI1
agammaglobulinemia 10

Mouse Phenotypes
abnormal chromosome number
abnormal cell cycle
abnormal granulocyte differentiation
abnormal neutrophil differentiation
abnormal macrophage differentiation
increased hematopoietic stem cell proliferation
Availability Mouse Genotype
Spi1tm1.3Dgt/Spi1tm1.3Dgt
Spi1tm1Ram/Spi1tm1Ram
Spi1tm4.1Dgt/Spi1tm4.1Dgt
Spi1tm1.2Nutt/Spi1tm1.2Nutt
Tg(Mx1-cre)1Cgn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory