|
Symbol Name ID |
Ccl2
chemokine (C-C motif) ligand 2 MGI:98259 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
abnormal dendritic cell chemotaxis |
abnormal macrophage chemotaxis |
impaired macrophage chemotaxis |
abnormal leukocyte migration |
decreased susceptibility to induced colitis |
increased neutrophil cell number |
decreased dendritic cell number |
increased CD4-positive, alpha beta T cell number |
decreased lymphocyte cell number |
decreased macrophage cell number |
increased osteoclast cell number |
decreased leukocyte cell number |
abnormal monocyte morphology |
abnormal neutrophil physiology |
increased IgG1 level |
increased IgG level |
abnormal T cell physiology |
abnormal macrophage physiology |
abnormal microglial cell physiology |
increased circulating interferon-gamma level |
increased circulating interleukin-10 level |
increased circulating tumor necrosis factor level |
abnormal chemokine level |
abnormal dendritic cell physiology |
decreased susceptibility to type IV hypersensitivity reaction |
abnormal cytokine secretion |
abnormal chemokine secretion |
decreased interferon-gamma secretion |
decreased interleukin-1 beta secretion |
increased interleukin-10 secretion |
decreased interleukin-12b secretion |
decreased interleukin-4 secretion |
decreased interleukin-5 secretion |
decreased susceptibility to experimental autoimmune encephalomyelitis |
decreased inflammatory response |
increased susceptibility to bacterial infection |
increased susceptibility to infection induced morbidity/mortality |
increased susceptibility to parasitic infection |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||
| Ccl2tm1.1Tyos/Ccl2tm1.1Tyos | ||||||||||||||||||||||||||||||||||||||||
| Ccl2tm1Lex/Ccl2tm1Lex | * | |||||||||||||||||||||||||||||||||||||||
| Ccl2tm1Rol/Ccl2tm1Rol | ||||||||||||||||||||||||||||||||||||||||
| Ccl2tm1Rol/Ccl2tm1Rol Tg(Ccr2-GFP)8Pam/0 |
||||||||||||||||||||||||||||||||||||||||
| Ccl2tm1Tyos/Ccl2tm1Tyos | ||||||||||||||||||||||||||||||||||||||||
| Ccl2tm1.1Pame/Ccl2tm1.1Pame Tg(Nes-cre)1Kln/0 (conditional) |
||||||||||||||||||||||||||||||||||||||||
| Ccl2tm1.1Pame/Ccl2tm1.1Pame Tg(Tek-cre)12Flv/0 (conditional) |
||||||||||||||||||||||||||||||||||||||||
| Ccl2tm1.1Pame/Ccl2tm1.1Pame Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
* | |||||||||||||||||||||||||||||||||||||||
| Ccl2tm1.1Pame/Ccl2tm1.1Pame Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
* | |||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support. |
last database update 02/16/2021 MGI 6.16 |
|
|
|
||
Analysis Tools