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Symbol
Name
ID
Ret
ret proto-oncogene
MGI:97902
Phenotype annotations related to renal/urinary system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Elevated urinary vanillylmandelic acid
Elevated urinary dopamine
Elevated urinary epinephrine
Elevated urinary norepinephrine
Proteinuria
Renal artery stenosis
Disease(s) Associated with RET
multiple endocrine neoplasia type 2A
multiple endocrine neoplasia type 2B
pheochromocytoma

Mouse Phenotypes
renal/urinary system phenotype
increased metanephric mesenchyme apoptosis
increased kidney apoptosis
abnormal kidney morphology
abnormal kidney collecting duct morphology
dilated renal glomerular capsule
abnormal renal glomerulus morphology
glomerulosclerosis
decreased renal glomerulus number
absent kidney cortex
abnormal kidney development
abnormal kidney medulla development
abnormal kidney mesenchyme morphology
abnormal metanephric mesenchyme morphology
absent nephrogenic zone
absent kidney medulla
hydronephrosis
decreased kidney weight
small kidney
kidney atrophy
renal hypoplasia
dilated renal tubules
renal cast
absent kidney
ectopic kidney
kidney cysts
single kidney
abnormal ureter morphology
abnormal ureter development
absent ureter
blind ureter
dilated ureter
large ureter
ureter obstruction
ureter stenosis
abnormal urinary bladder morphology
abnormal ureteric bud morphology
abnormal branching involved in ureteric bud morphogenesis
impaired branching involved in ureteric bud morphogenesis
abnormal ureteric bud elongation
abnormal ureteric bud invasion
ectopic ureteric bud
Availability Mouse Genotype
Rettm1.2Pern/Rettm1.2Pern
Rettm1Cos/Rettm1Cos
Rettm1Cti/Rettm1Cti
Rettm1Giro/Rettm1Giro
Rettm1Jmi/Rettm1Jmi
Rettm1Mat/Rettm1Mat
Rettm2.1Heno/Rettm2.1Heno
Rettm2Cos/Rettm2Cos
Rettm3(RET)Vpa/Rettm3(RET)Vpa
Rettm4(RET)Jmi/Rettm4(RET)Jmi
Rettm5(RET)Vpa/Rettm5(RET)Vpa
Rettm7(RET)Jmi/Rettm7(RET)Jmi
Rettm8(RET)Jmi/Rettm8(RET)Jmi
Rettm9(RET)Jmi/Rettm9(RET)Jmi
Rettm10(RET)Jmi/Rettm10(RET)Jmi *
Rettm11(RET)Jmi/Rettm11(RET)Jmi
Rettm12(RET)Jmi/Rettm12(RET)Jmi
Rettm13.1Jmi/Rettm13.1Jmi
Rettm1Cos/Ret+
Rettm1Jmi/Ret+
Rettm2(RET)Heno/Rettm3.1(Bcl2l1)Heno
Rettm3.1(RET)Jmi/Ret+
Rettm9(RET)Jmi/Rettm12(RET)Jmi *
Nkx6-2tm2(cre)Ercs/Nkx6-2+
Rettm1.1Pern/Rettm1.1Pern  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory