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Symbol
Name
ID
Ret
ret proto-oncogene
MGI:97902
Phenotype annotations related to digestive/alimentary system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Colonic diverticula
Enterocolitis
Abnormality of enteric ganglion morphology
Aganglionic megacolon
Intestinal obstruction
Intestinal polyposis
Constipation
Diarrhea
Nausea and vomiting
Vomiting
Functional abnormality of the gastrointestinal tract
Disease(s) Associated with RET
congenital central hypoventilation syndrome
Hirschsprung's disease
multiple endocrine neoplasia type 2A
multiple endocrine neoplasia type 2B

Mouse Phenotypes
digestive/alimentary phenotype
abnormal large intestine morphology
abnormal colon morphology
aganglionic megacolon
abnormal small intestine morphology
distended ileum
enlarged ileum
abnormal jejunum morphology
abnormal submandibular gland morphology
abnormal defecation
abnormal feces composition
abnormal intestinal peristalsis
intestinal hypoperistalsis
Availability Mouse Genotype
Rettm1Cos/Rettm1Cos
Rettm1Jmi/Rettm1Jmi
Rettm1Mat/Rettm1Mat
Rettm2Cos/Rettm2Cos
Rettm3(RET)Vpa/Rettm3(RET)Vpa
Rettm3Cos/Rettm3Cos
Rettm1Cos/Ret+
Rettm1Cti/Ret+
Rettm3.1(Bcl2l1)Heno/Ret+ *
Rettm3.1(RET)Jmi/Ret+
Rettm1Ddg/Rettm1Ddg
H2afvTg(Wnt1-cre)11Rth/0  (conditional)
Rettm1Heno/Rettm3.1(Bcl2l1)Heno
Tg(CAG-cre/Esr1*)5Amc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory