Symbol
Name
ID

Ren1
renin 1 structural
MGI:97898

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hyperuricemia	Proteinuria
Disease(s) Associated with REN	Hyperuricemia	Proteinuria
familial juvenile hyperuricemic nephropathy

Mouse Phenotypes

homeostasis/metabolism phenotype

increased circulating creatinine level

abnormal blood homeostasis

increased blood urea nitrogen level

decreased circulating angiotensin II level

increased circulating aldosterone level

increased circulating potassium level

decreased circulating renin level

dehydration

metabolic acidosis

abnormal urine homeostasis

decreased urine osmolality

decreased physiological sensitivity to xenobiotic

Availability

Mouse Genotype

Ren1^tm1.2Sig/Ren1^tm1.2Sig

Ren1^tm1Afu/Ren1^tm1Afu

Ren1^tm1Bjm/Ren1^tm1Bjm

Ren1^tm1Gom/Ren1^tm1Gom

Ren1^tm1Mgfs/Ren1^tm1Mgfs

Ren1^tm1Tkh/Ren1^tm1Tkh

Ren1^tm3Gom/Ren1^tm3Gom

Ren1^tm3Gom/Ren1⁺

Ren1^tm1.1Sig/Ren1^tm1.1Sig
Tg(GFAP-cre)25Mes/0 (conditional)

Ren1^tm1.1Sig/Ren1^tm1.1Sig
Tg(Nes-cre)1Kln/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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