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Symbol
Name
ID
Rb1
RB transcriptional corepressor 1
MGI:97874
Phenotype annotations related to vision/eye
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Vitreous hemorrhage
Leukocoria
Retinoblastoma
Retinal calcification
Vitritis
Disease(s) Associated with RB1
osteosarcoma
retinoblastoma

Mouse Phenotypes
vision/eye phenotype
increased lens fiber apoptosis
abnormal retina apoptosis
decreased retina apoptosis
increased retina apoptosis
decreased retina ganglion cell number
decreased retina photoreceptor cell number
decreased retina rod cell number
absent retina bipolar cells
abnormal retina horizontal cell morphology
abnormal lens development
abnormal lens fiber morphology
cataract
abnormal retina morphology
abnormal retina ganglion layer morphology
abnormal retina inner nuclear layer morphology
thin retina inner nuclear layer
disorganized retina inner nuclear layer
abnormal retina inner plexiform layer morphology
thin retina inner plexiform layer
thin retina outer nuclear layer
Availability Mouse Genotype
Rb1tm1.1Jyjw/Rb1tm1.1Jyjw
Rb1tm1Brd/Rb1tm1Brd *
Rb1tm1Dwg/Rb1tm1Dwg
Rb1tm1Jyjw/Rb1tm1Jyjw
Rb1tm1Mlh/Rb1tm1Mlh *
Rb1tm1Tyj/Rb1tm1Tyj *
Rb1tm1Tyj/Rb1tm1Tyj
Tg(Rb1)1Blg/0
Rb1tm2Mlh/Rb1tm2Mlh *
Rb1tm1.1Jyjw/Rb1+
Rb1tm1Jyjw/Rb1+
Rb1tm1Tyj/Rb1tm2Tyj *
Rb1tm2Brn/Rb1tm2Brn
Tg(Rbp3-cre)1Brn/0  (conditional)
*
Rb1tm3Tyj/Rb1tm3Tyj
Tg(Pax6-cre,GFP)2Pgr/0  (conditional)
Rb1tm3Tyj/Rb1tm3Tyj
Tg(Nes-cre)1Atp/0  (conditional)
Rb1tm1Dwg/Rb1tm2Brn
Tg(Chx10-EGFP/cre,-ALPP)2Clc/0  (conditional)
Rb1tm3Tyj/Rb1tm3.1Tyj
Tg(Nes-cre)1Atp/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory