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Symbol
Name
ID
Ptgs2
prostaglandin-endoperoxide synthase 2
MGI:97798
Phenotype annotations related to skeleton
Darker colors indicate more annotations
Human Phenotypes
Sinusitis
Chronic sinusitis
Interphalangeal joint erosions
Clubbing of fingers
Swan neck-like deformities of the fingers
Joint swelling
Joint stiffness
Back pain
Osteopenia
Osteoporosis
Bone cyst
Rheumatoid arthritis
Polyarticular arthritis
Digital flexor tenosynovitis
Disease(s) Associated with PTGS2
cystic fibrosis
idiopathic pulmonary fibrosis
pancreatic cancer
rheumatoid arthritis
sarcoidosis

Mouse Phenotypes
abnormal osteoclast differentiation
abnormal bone healing
decreased susceptibility to induced arthritis
abnormal endochondral bone ossification
Availability Mouse Genotype
Ptgs2tm1Unc/Ptgs2tm1Unc
Ptgs2tm1Unc/Ptgs2+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory