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Symbol
Name
ID
Ptgs2
prostaglandin-endoperoxide synthase 2
MGI:97798
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
abnormal osteoclast differentiation
increased susceptibility to induced colitis
peritoneal inflammation
abnormal class switch recombination
abnormal memory B cell differentiation
increased leukocyte cell number
enlarged spleen
spleen hyperplasia
decreased IgG1 level
decreased IgG2a level
decreased IgG3 level
increased IgM level
abnormal macrophage physiology
abnormal mesenteric lymph node morphology
increased tumor necrosis factor secretion
decreased susceptibility to induced arthritis
decreased susceptibility to endotoxin shock
increased susceptibility to endotoxin shock
kidney inflammation
pyelonephritis
tubulointerstitial nephritis
abnormal response to infection
Availability Mouse Genotype
Ptgs2tm1.1Fun/Ptgs2tm1.1Fun
Ptgs2tm1.1Wls/Ptgs2tm1.1Wls
Ptgs2tm1Jed/Ptgs2tm1Jed *
Ptgs2tm1Unc/Ptgs2tm1Unc *
Ptgs2tm1Unc/Ptgs2+
Ptgs2tm1Unc/Ptgs2tm2.1Hahe

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory