Symbol
Name
ID

Pparg
peroxisome proliferator activated receptor gamma
MGI:97747

Phenotype annotations related to skeleton

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Coronal craniosynostosis	Decreased calvarial ossification	Micrognathia	Malar flattening	Brachydactyly	Bent long bone	Hypoplastic pubic bone	Short clavicles	Bell-shaped thorax	Back pain
Disease(s) Associated with PPARG	Coronal craniosynostosis	Decreased calvarial ossification	Micrognathia	Malar flattening	Brachydactyly	Bent long bone	Hypoplastic pubic bone	Short clavicles	Bell-shaped thorax	Back pain
pancreatic cancer
pre-eclampsia

Mouse Phenotypes

skeleton phenotype

abnormal osteoblast differentiation

abnormal osteoclast differentiation

decreased osteoclast cell number

abnormal osteoclast morphology

increased susceptibility to induced arthritis

abnormal bone structure

abnormal bone marrow cavity morphology

abnormal bone marrow morphology

increased bone mineral density

increased trabecular bone volume

increased bone volume

increased osteoblast cell number

abnormal trabecular bone morphology

abnormal bone trabecula morphology

increased bone trabecula number

increased trabecular bone mass

increased trabecular bone thickness

abnormal bone ossification

Availability

Mouse Genotype

Pparg^tm1.1Auw/Pparg^tm1.1Auw

Pparg^tm1Tka/Pparg⁺

Pparg^tm2Rev/Pparg^tm2Rev
Tg(Tek-cre)1Ywa/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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