Symbol Name ID |
Pparg
peroxisome proliferator activated receptor gamma MGI:97747 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Coronal craniosynostosis |
Decreased calvarial ossification |
Micrognathia |
Malar flattening |
Brachydactyly |
Bent long bone |
Hypoplastic pubic bone |
Short clavicles |
Bell-shaped thorax |
Back pain |
Disease(s) Associated with PPARG | ||||||||||
pancreatic cancer | ||||||||||
pre-eclampsia |
Mouse Phenotypes | skeleton phenotype |
abnormal osteoblast differentiation |
abnormal osteoclast differentiation |
decreased osteoclast cell number |
abnormal osteoclast morphology |
increased susceptibility to induced arthritis |
abnormal bone structure |
abnormal bone marrow cavity morphology |
abnormal bone marrow morphology |
increased bone mineral density |
increased trabecular bone volume |
increased bone volume |
increased osteoblast cell number |
abnormal trabecular bone morphology |
abnormal bone trabecula morphology |
increased bone trabecula number |
increased trabecular bone mass |
increased trabecular bone thickness |
abnormal bone ossification |
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Availability | Mouse Genotype | |||||||||||||||||||
Ppargtm1.1Auw/Ppargtm1.1Auw | ||||||||||||||||||||
Ppargtm1Tka/Pparg+ | * | |||||||||||||||||||
Ppargtm2Rev/Ppargtm2Rev Tg(Tek-cre)1Ywa/? (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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