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Symbol
Name
ID 		Pparg
peroxisome proliferator activated receptor gamma
MGI:97747
Phenotype annotations related to integument
Darker colors indicate more annotations
Human Phenotypes
Breast carcinoma
Prominent superficial veins
Prominent veins on trunk
Jaundice
Hirsutism
Generalized hirsutism
Reduced subcutaneous adipose tissue
Aplasia/Hypoplasia of the skin
Thin skin
Xanthomatosis
Acanthosis nigricans
Disease(s) Associated with PPARG
familial partial lipodystrophy type 3
pancreatic cancer
pre-eclampsia

Mouse Phenotypes
absent subcutaneous adipose tissue
decreased subcutaneous adipose tissue amount
abnormal mammary gland growth during pregnancy
abnormal mammary gland alveolus morphology
abnormal skin sebaceous gland morphology
sebaceous gland atrophy
skin inflammation
abnormal skin adnexa morphology
abnormal coat appearance
premature hair loss
progressive hair loss
matted coat
abnormal hair follicle morphology
abnormal hair follicle ostium morphology
abnormal hair cycle
abnormal hair cycle anagen phase
abnormal hair shedding
abnormal skin morphology
hyperkeratosis
abnormal keratinocyte morphology
abnormal skin appearance
flaky skin
reddish skin
skin fibrosis
Availability Mouse Genotype
Ppargtm2(tTA)Yba/Pparg+
Ppargtm3(tTA)Yba/Pparg+
Ppargtm1.2Mtz/Ppargtm1.2Mtz
Tg(Krt10-cre/ERT2)1Pcn/0  (conditional)
Ppargtm1Gonz/Ppargtm1Gonz
Tg(MMTV-cre)1Mam/?  (conditional)
Ppargtm2Rev/Ppargtm2Rev
Tg(Tek-cre)1Ywa/?  (conditional)
Ppargtm2Rev/Ppargtm2Rev
Tg(Krt1-15-cre/PGR*)22Cot/?  (conditional)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory