|
Symbol Name ID |
Pomc
pro-opiomelanocortin-alpha MGI:97742 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Splenomegaly |
Ascites |
Hepatomegaly |
Peritonitis |
Increased waist to hip ratio |
Obesity |
| Disease(s) Associated with POMC | ||||||
| familial mediterranean fever | ||||||
| obesity |
| Mouse Phenotypes | increased body fat mass |
growth/size/body region phenotype |
increased lean body mass |
increased body weight |
obese |
increased body length |
abnormal body weight |
increased susceptibility to weight gain |
increased susceptibility to diet-induced obesity |
increased liver weight |
enlarged spleen |
|
| Availability | Mouse Genotype | |||||||||||
| Pomctm1.1Kgm/Pomctm1.1Kgm | ||||||||||||
| Pomctm1Low/Pomctm1Low | ||||||||||||
| Pomctm1Low/Pomctm1Low Tg(Pomc)#Low/0 |
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| Pomctm1Low/Pomctm1Low Tg(Pomc)#Low/Tg(Pomc)#Low |
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| Pomctm1Sora/Pomctm1Sora | ||||||||||||
| Pomctm2.1Low/Pomctm2.1Low | * | |||||||||||
| Pomctm2Low/Pomctm2Low | ||||||||||||
| Pomctm2Ute/Pomctm2Ute | ||||||||||||
| Pomcem1(IMPC)Rbrc/Pomc+ | ||||||||||||
| Pomctm1Sora/Pomc+ | ||||||||||||
| Pomctm2Ute/Pomc+ | * | |||||||||||
| Tg(Pomc)#Low/0 | * | |||||||||||
| Pomctm2Low/Pomctm2Low Tg(CAG-cre/Esr1*)5Amc/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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