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Symbol
Name
ID
Plcb1
phospholipase C, beta 1
MGI:97613
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Spasticity
Hypsarrhythmia
Hyperreflexia
Epileptic encephalopathy
Focal-onset seizure
Generalized-onset seizure
Disease(s) Associated with PLCB1
early infantile epileptic encephalopathy 12

Mouse Phenotypes
increased susceptibility to pharmacologically induced seizures
convulsive seizures
abnormal brain size
loss of hippocampal neurons
abnormal excitatory postsynaptic currents
decreased prepulse inhibition
Availability Mouse Genotype
Plcb1Tg(LGB)56Mbal/Plcb1Tg(LGB)56Mbal
Plcb1tm1Hssh/Plcb1tm1Hssh

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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Funding Information
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory