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Symbol
Name
ID
Pkd1
polycystin 1, transient receptor poteintial channel interacting
MGI:97603
Phenotype annotations related to skeleton
Darker colors indicate more annotations

Mouse Phenotypes
abnormal osteoblast differentiation
impaired osteoblast differentiation
decreased chondrocyte proliferation
increased osteoblast proliferation
abnormal craniofacial bone morphology
abnormal sagittal suture morphology
abnormal basicranium morphology
abnormal presphenoid synchondrosis
premature presphenoid synchondrosis closure
abnormal sphenooccipital synchondrosis
premature sphenooccipital synchondrosis closure
premature cranial synchondrosis closure
short frontal bone
abnormal sphenoid bone morphology
short presphenoid bone
malocclusion
short mandible
short premaxilla
maxilla hypoplasia
short maxilla
micrognathia
nasal bone hypoplasia
short nasal bone
domed cranium
abnormal Meckel's cartilage morphology
spina bifida occulta
abnormal radius morphology
abnormal ulna morphology
short femur
abnormal thyroid cartilage morphology
decreased width of hypertrophic chondrocyte zone
decreased length of long bones
abnormal spine curvature
abnormal vertebrae morphology
abnormal bone marrow cavity morphology
abnormal bone marrow morphology
decreased bone mineral density
decreased trabecular bone volume
abnormal compact bone morphology
decreased compact bone mass
decreased compact bone thickness
decreased trabecular bone mass
abnormal cartilage development
abnormal perichondrium morphology
abnormal skeleton development
chondrodystrophy
abnormal bone mineralization
decreased bone mineralization
delayed endochondral bone ossification
delayed intramembranous bone ossification
delayed bone ossification
Availability Mouse Genotype
Pkd1b2b1585Clo/Pkd1b2b1585Clo
Pkd1tm1Hung/Pkd1tm1Hung
Pkd1tm1Jzh/Pkd1tm1Jzh
Pkd1tm1Rsa/Pkd1tm1Rsa
Pkd1tm2Jzh/Pkd1tm2Jzh
Pkd1tm1Shh/Pkd1tm1.1Pcha
Tg(Pkd1)26Mtru/0
Pkd1tm2Ggg/Pkd1tm2Ggg
Tg(Col1a1-cre)1Bek/0  (conditional)
Pkd1tm3Jzh/Pkd1tm3Jzh
H2afvTg(Wnt1-cre)11Rth/?  (conditional)
Pkd1tm3Jzh/Pkd1tm3Jzh  (conditional)
Pkd1tm3Jzh/Pkd1tm3Jzh
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/?  (conditional)
Pkd1tm3Jzh/Pkd1tm3Jzh
Tg(Col2a1-cre)10Amc/0  (conditional)
Pkd1tm1Ggg/Pkd1tm2Ggg
Tg(Col1a1-cre)1Bek/0  (conditional)
Pkd1tm2Ggg/Pkd1+
Tg(Col1a1-cre)1Bek/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory