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Symbol
Name
ID
Pkd1
polycystin 1, transient receptor poteintial channel interacting
MGI:97603
Phenotype annotations related to cellular
Darker colors indicate more annotations

Mouse Phenotypes
increased kidney epithelial cell primary cilium length
abnormal peroxisome morphology
abnormal mitotic spindle morphology
increased kidney apoptosis
increased renal tubule apoptosis
abnormal osteoblast differentiation
impaired osteoblast differentiation
decreased chondrocyte proliferation
increased kidney cell proliferation
increased osteoblast proliferation
increased cell proliferation
increased hepatocyte proliferation
abnormal kidney epithelial cell primary cilium physiology
decreased fatty acid oxidation
oxidative stress
Availability Mouse Genotype
Pkd1tm1Jzh/Pkd1tm1Jzh
Pkd1tm1.2Djmp/Pkd1+
Pkd1tm1Shh/Pkd1tm1.1Pcha
Tg(Pkd1)6Mtru/0
Tg(Pkd1)26Mtru/0
Pkd1tm2Ggg/Pkd1tm2Ggg
Tg(Nes-cre)Wme/0  (conditional)
Pkd1tm2Ggg/Pkd1tm2Ggg
Tg(Col1a1-cre)1Bek/0  (conditional)
Pkd1tm2Ggg/Pkd1tm2Ggg
Tg(Hoxb7-cre)13Amc/0  (conditional)
Pkd1tm2Som/Pkd1tm2Som
Tg(Cdh16-cre)91Igr/0  (conditional)
Pkd1tm3Jzh/Pkd1tm3Jzh
Tg(Ggt1-cre)M3Egn/0  (conditional)
Pkd1tm3Jzh/Pkd1tm3Jzh
H2afvTg(Wnt1-cre)11Rth/?  (conditional)
Pkd1tm3Jzh/Pkd1tm3Jzh  (conditional)
Pkd1tm1.1Djmp/Pkd1tm1.2Djmp
Tg(Cdh16-cre/ERT2)F427Djmp/0  (conditional)
Pkd1tm1.1Pcha/Pkd1tm2Som
Tg(Cdh16-cre)91Igr/0  (conditional)
Pkd1tm1Som/Pkd1tm2Som
Tg(Cdh16-cre/ERT2)24Igr/?  (conditional)
Pkd1tm2Ggg/Pkd1+
Tg(Col1a1-cre)1Bek/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory