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protein kinase C, theta
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
decreased T cell apoptosis
increased T cell apoptosis
decreased T cell proliferation
decreased splenocyte proliferation
decreased DN1 thymic pro-T cell number
abnormal T-helper 1 cell differentiation
abnormal positive T cell selection
decreased CD4-positive, alpha beta T cell number
decreased CD8-positive, alpha-beta T cell number
decreased NK T cell number
abnormal effector T cell morphology
decreased IgG level
abnormal T cell physiology
abnormal CD4-positive, alpha-beta T cell physiology
abnormal T-helper 2 physiology
abnormal T cell activation
impaired humoral immune response
decreased interferon-gamma secretion
decreased interleukin-13 secretion
decreased interleukin-17 secretion
decreased interleukin-2 secretion
decreased interleukin-4 secretion
decreased interleukin-5 secretion
decreased susceptibility to experimental autoimmune encephalomyelitis
abnormal response to infection
Availability Mouse Genotype
Prkcqtm1Litt/Prkcqtm1Litt *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory