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Symbol
Name
ID

Prkaca
protein kinase, cAMP dependent, catalytic, alpha
MGI:97592

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Diabetes mellitus	Decreased circulating ACTH concentration	Decreased circulating dehydroepiandrosterone concentration	Increased serum testosterone level	Increased circulating cortisol level	Primary hypercortisolism	Paradoxical increased cortisol secretion on dexamethasone suppression test	Increased urinary cortisol level
Disease(s) Associated with PRKACA
primary pigmented nodular adrenocortical disease

Mouse Phenotypes		decreased insulin secretion	increased circulating glucose level	decreased circulating insulin level	increased circulating triglyceride level	abnormal glucose homeostasis	impaired glucose tolerance	abnormal glycogen homeostasis	decreased liver glycogen level	decreased urine protein level	abnormal enzyme/coenzyme activity
Availability	Mouse Genotype	decreased insulin secretion	increased circulating glucose level	decreased circulating insulin level	increased circulating triglyceride level	abnormal glucose homeostasis	impaired glucose tolerance	abnormal glycogen homeostasis	decreased liver glycogen level	decreased urine protein level	abnormal enzyme/coenzyme activity
	Prkaca^tm1Gsm/Prkaca^tm1Gsm
	Tg(Camk2a-Prkaca)426Tabe/0
	Prkaca^tm3Gsm/Prkaca^tm3Gsm Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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