Symbol
Name
ID

Abcb1a
ATP-binding cassette, sub-family B member 1A
MGI:97570

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes

Pedal edema

Hyperbilirubinemia

Elevated circulating C-reactive protein concentration

Elevated circulating amyloid A concentration

Reduced leukocyte alkaline phosphatase

Elevated erythrocyte sedimentation rate

Type II diabetes mellitus

Insulin resistance

Pleural effusion

Fever

Recurrent fever

Decreased level of D-mannose in urine

Proteinuria

Amyloidosis

Renal amyloidosis

Ascites

Disease(s) Associated with ABCB1

Behcet's disease

chronic myeloid leukemia

familial mediterranean fever

malaria

type 2 diabetes mellitus

Mouse Phenotypes		increased susceptibility to ototoxicity-induced hearing loss	increased physiological sensitivity to xenobiotic	abnormal xenobiotic pharmacokinetics
Availability	Mouse Genotype		increased physiological sensitivity to xenobiotic	abnormal xenobiotic pharmacokinetics
	Abcb1a^mds/Abcb1a^mds
	Abcb1a^tm1Bor/Abcb1a^tm1Bor
	Abcb1b^tm2Bor/Abcb1b^tm2Bor

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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