About Help FAQ

Symbol
Name
ID

Prf1
perforin 1 (pore forming protein)
MGI:97551

Phenotype annotations related to neoplasm

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Lymphoma
Disease(s) Associated with PRF1	Lymphoma
non-Hodgkin lymphoma

Mouse Phenotypes		increased T cell derived lymphoma incidence	abnormal tumor morphology	increased tumor growth/size	increased lymphoma incidence	increased B cell derived lymphoma incidence	increased lung adenocarcinoma incidence	increased sarcoma incidence	increased incidence of induced tumors	decreased tumor latency	increased tumor latency
Availability	Mouse Genotype	increased T cell derived lymphoma incidence	abnormal tumor morphology	increased tumor growth/size	increased lymphoma incidence	increased B cell derived lymphoma incidence	increased lung adenocarcinoma incidence	increased sarcoma incidence	increased incidence of induced tumors	decreased tumor latency	increased tumor latency
	Prf1^tm1Sdz/Prf1^tm1Sdz									!
	Prf1^tm1Tsc/Prf1^tm1Tsc
	Prf1^tm1Sdz/Prf1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23