Symbol Name ID |
Pdha1
pyruvate dehydrogenase E1 alpha 1 MGI:97532 |
Darker colors indicate more annotations |
Human Phenotypes | Decreased activity of the pyruvate dehydrogenase complex |
Increased serum pyruvate |
Hyperalaninemia |
Hyperammonemia |
Abnormal CSF pyruvate family amino acid concentration |
Increased CSF lactate |
Chronic lactic acidosis |
Increased circulating lactate concentration |
Lactic acidosis |
Congenital lactic acidosis |
Severe lactic acidosis |
Metabolic acidosis |
Disease(s) Associated with PDHA1 | ||||||||||||
pyruvate decarboxylase deficiency |
Mouse Phenotypes | increased circulating insulin level |
|
Availability | Mouse Genotype | |
Pdha1tm1Ptl/Pdha1+ Tg(Ckmm-cre)5Khn/0 (conditional) |
||
Pdha1tm1Ptl/Y Tg(Ckmm-cre)5Khn/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 03/19/2024 MGI 6.23 |
|
|