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Symbol
Name
ID
Pbx1
pre B cell leukemia homeobox 1
MGI:97495
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal thymus morphology
small thymus
thymus hypoplasia
ectopic thymus
abnormal definitive hematopoiesis
decreased common myeloid progenitor cell number
absent common myeloid progenitor cells
decreased pro-B cell number
decreased double-negative T cell number
anemia
impaired hematopoiesis
decreased bone marrow cell number
abnormal common lymphocyte progenitor cell morphology
low mean erythrocyte cell number
decreased hematocrit
decreased mature B cell number
decreased B cell number
decreased pre-B cell number
decreased CD4-positive, alpha beta T cell number
decreased CD8-positive, alpha-beta T cell number
decreased T cell number
decreased hematopoietic stem cell number
abnormal hematopoietic stem cell morphology
abnormal spleen morphology
abnormal spleen mesenchyme morphology
small spleen
spleen hypoplasia
absent spleen
Availability Mouse Genotype
Pbx1tm1Mlc/Pbx1tm1Mlc
Pbx1tm1Mlc/Pbx1tm2.1Mlc
Nkx2-5tm2(cre)Rph/Nkx2-5+
Pbx1tm1.1Koss/Pbx1tm1.1Koss  (conditional)
Pbx1tm1.1Koss/Pbx1tm1.1Koss
Tg(WT1-cre)AG11Dbdr/0  (conditional)
Pbx1tm1Koss/Pbx1tm1Koss
Nkx2-5tm2(cre)Rph/Nkx2-5+  (conditional)
Pbx1tm1.1Koss/Pbx1tm1.2Koss
Tmem163Tg(ACTB-cre)2Mrt/0  (conditional)
Pbx1tm1Mlc/Pbx1tm3.1Mlc
Tg(Tek-cre)1Ywa/0  (conditional)
Pbx1tm1Mlc/Pbx1tm3.1Mlc
Tg(Mx1-cre)1Cgn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory