Symbol
Name
ID

Pax7
paired box 7
MGI:97491

Phenotype annotations related to muscle

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Facial hypotonia	Congenital contracture	Axial hypotonia	Infantile axial hypotonia	Generalized hypotonia	Muscle weakness	Respiratory insufficiency due to muscle weakness	Skeletal muscle atrophy	Alveolar rhabdomyosarcoma
Disease(s) Associated with PAX7	Facial hypotonia	Congenital contracture	Axial hypotonia	Infantile axial hypotonia	Generalized hypotonia	Muscle weakness	Respiratory insufficiency due to muscle weakness	Skeletal muscle atrophy	Alveolar rhabdomyosarcoma
alveolar rhabdomyosarcoma
congenital myopathy 19

Mouse Phenotypes

muscle phenotype

skeletal muscle necrosis

abnormal skeletal muscle satellite cell proliferation

abnormal muscle morphology

decreased skeletal muscle fiber diameter

decreased skeletal muscle fiber number

decreased skeletal muscle weight

abnormal skeletal muscle morphology

thin diaphragm muscle

decreased skeletal muscle size

decreased satellite cell number

skeletal muscle fibrosis

abnormal muscle regeneration

impaired skeletal muscle regeneration

muscle weakness

Availability

Mouse Genotype

Pax7^{tm1.1(rtTA)Sjl}/Pax7^{tm1.1(rtTA)Sjl}

Pax7^tm1.2Fan/Pax7^tm1.2Fan

Pax7^tm1Pgr/Pax7^tm1Pgr

Pax7^tm2Pgr/Pax7^tm2Pgr

Pax7^tm1.1Thbr/Pax7^tm1.1Thbr
Tg(CMV-cre)1Cgn/0 (conditional)

Pax7^tm1.1Thbr/Pax7^tm1.1Thbr (conditional)

Pax7^tm1.1Thbr/Pax7^tm1.1Thbr
Myf5^tm1(cre)Mrc/Myf5⁺ (conditional)

Pax7^tm1.1Thbr/Pax7^tm1.1Thbr
Myf5^tm3(cre)Sor/Myf5⁺ (conditional)

Pax7^tm1.1Thbr/Pax7^{tm2.1(cre/ERT2)Fan} (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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