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Symbol
Name
ID
Oprm1
opioid receptor, mu 1
MGI:97441
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Negativism
Addictive alcohol use
Fatigue
Arthralgia
Disease(s) Associated with OPRM1
alcohol dependence
rheumatoid arthritis
schizophrenia

Mouse Phenotypes
behavior/neurological phenotype
abnormal behavioral response to addictive substance
enhanced behavioral response to cocaine
enhanced behavioral response to morphine
impaired behavioral response to morphine
decreased behavioral withdrawal response
enhanced behavioral response to addictive substance
enhanced behavioral response to anesthetic
impaired behavioral response to anesthetic
enhanced conditioned place preference behavior
abnormal operant conditioning behavior
abnormal spatial learning
increased coping response
increased vertical activity
decreased locomotor activity
induced hyperactivity
abnormal touch/ nociception
abnormal pain threshold
abnormal chemically-elicited antinociception
decreased chemically-elicited antinociception
increased chemically-elicited antinociception
decreased thermal nociceptive threshold
increased thermal nociceptive threshold
reduced male mating frequency
abnormal social investigation
Availability Mouse Genotype
Oprm1IAP/Oprm1IAP
Oprm1tm1.1Jbwa/Oprm1tm1.1Jbwa
Oprm1tm1Jep/Oprm1tm1Jep
Oprm1tm1Jlw/Oprm1tm1Jlw
Oprm1tm1Kff/Oprm1tm1Kff
Oprm1tm1Lex/Oprm1tm1Lex
Oprm1tm1Loh/Oprm1tm1Loh
Oprm1tm1Lyu/Oprm1tm1Lyu
Oprm1tm1Shlz/Oprm1tm1Shlz
Oprm1tm1Uhl/Oprm1tm1Uhl
Oprm1tm1Yxp/Oprm1tm1Yxp
Oprm1tm2.1Loh/Oprm1tm2.1Loh
Oprm1tm1Jep/Oprm1+
Oprm1tm1Loh/Oprm1+
Oprm1tm1Lyu/Oprm1+
Oprm1tm1Uhl/Oprm1+
Oprm1tm1.1Cgrf/Oprm1tm1.1Cgrf
Scn10atm2(cre)Jwo/Scn10a+  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory