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Symbol
Name
ID
Notch2
notch 2
MGI:97364
Phenotype annotations related to growth/size/body
Darker colors indicate more annotations
Human Phenotypes
Short neck
Hepatomegaly
Inguinal hernia
Umbilical hernia
Delayed puberty
Short stature
Failure to thrive
Intrauterine growth retardation
Disease(s) Associated with NOTCH2
Alagille syndrome
Hajdu-Cheney syndrome

Mouse Phenotypes
abnormal tooth morphology
abnormal olfactory epithelium morphology
embryonic growth retardation
ovarian follicular cyst
abnormal body composition
decreased body weight
renal glomerulus cyst
decreased body size
increased spleen weight
Availability Mouse Genotype
Notch2tm1Grid/Notch2tm1Grid
Notch2tm1Yha/Notch2tm1Yha
Notch2tm2Grid/Notch2tm2Grid
Notch2tm3.1Grid/Notch2tm3.1Grid
Notch2tm1.1Ecan/Notch2+
Notch2tm1.1Hhtg/Notch2+
Notch2tm3Grid/Notch2tm3Grid
Foxg1tm1(cre)Skm/Foxg1+  (conditional)
Notch2tm3Grid/Notch2tm3Grid
Tg(Tpbpa-cre,-EGFP)5Jcc/0  (conditional)
Gt(ROSA)26Sortm2(CAG-Notch2*)Uzs/Gt(ROSA)26Sor+
Cd19tm1(cre)Cgn/Cd19+  (conditional)
Gt(ROSA)26Sortm2(Notch2)Ryn/Gt(ROSA)26Sor+
Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+  (conditional)
Notch2tm2Grid/Notch2tm3Grid
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
Notch2tm3Grid/Notch2tm3.1Grid
Pax3tm1(cre)Joe/Pax3+  (conditional)
Notch2tm3Grid/Notch2tm3.1Grid
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory