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Symbol
Name
ID
Notch1
notch 1
MGI:97363
Phenotype annotations related to neoplasm
Darker colors indicate more annotations
Human Phenotypes
Cavernous hemangioma
Disease(s) Associated with NOTCH1
Adams-Oliver syndrome

Mouse Phenotypes
increased T cell derived lymphoma incidence
increased cholangiocarcinoma incidence
increased hemangioma incidence
increased leukemia incidence
increased liposarcoma incidence
Availability Mouse Genotype
Tg(LckNotch1)9Erob/?
Albtm1(cre/ERT2)Mtz/Alb+
Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+  (conditional)
Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+
Tg(Mx1-cre)1Cgn/0  (conditional)
Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+
Tg(Adipoq-cre)1Evdr/0  (conditional)
Notch1tm2Rko/Notch1tm3(cre)Rko  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory