|
Symbol Name ID |
Notch1
notch 1 MGI:97363 |
| Darker colors indicate more annotations |
| Human Phenotypes | Low anterior hairline |
Single transverse palmar crease |
Supernumerary nipple |
Cutis marmorata |
Alopecia |
Sparse hair |
Hypoplastic fingernail |
Hypoplastic fifth fingernail |
Aplastic/hypoplastic toenail |
Absent toenail |
Hypoplastic toenails |
Dystrophic toenail |
Toenail dysplasia |
Absent fingernail |
Small nail |
Aplasia/Hypoplasia of the skin |
Aplasia cutis congenita |
Aplasia cutis congenita over posterior parietal area |
Aplasia cutis congenita on trunk or limbs |
Cutis marmorata telangiectatica congenita |
| Disease(s) Associated with NOTCH1 | ||||||||||||||||||||
| Adams-Oliver syndrome |
| Mouse Phenotypes | Meibomian gland degeneration |
small sebaceous gland |
diluted coat color |
abnormal hair growth |
alopecia |
short hair |
waved hair |
abnormal hair shaft morphology |
abnormal hair follicle morphology |
disorganized inner root sheath cells |
|
| Availability | Mouse Genotype | ||||||||||
| Notch1tm1Agt/Notch1tm1Agt Tg(Tyr-cre)2Lru/0 (conditional) |
|||||||||||
| Notch1tm2Rko/Notch1tm2Rko Tg(Msx2-cre)5Rem/0 (conditional) |
|||||||||||
| Notch1tm2Rko/Notch1tm2Rko Tg(KRT14-rtTA)F42Efu/0 Tg(tetO-cre)1Jaw/0 (conditional) |
|||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/09/2024 MGI 6.23 |
|
|
|
||
Analysis Tools