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Symbol
Name
ID
Notch1
notch 1
MGI:97363
Phenotype annotations related to craniofacial
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Micrognathia
Microcephaly
Macrocephaly
Calvarial skull defect
Encephalocele
Low anterior hairline
Cleft upper lip
Cleft palate
Bulbous nose
Depressed nasal bridge
Blepharophimosis
Narrow palpebral fissure
Short palpebral fissure
Disease(s) Associated with NOTCH1
Adams-Oliver syndrome

Mouse Phenotypes
craniofacial phenotype
thick neurocranium
small pharyngeal arch
Availability Mouse Genotype
Notch1sot/Notch1sot
Notch1tm2Rko/Notch1tm2Rko
H2afvTg(Wnt1-cre)11Rth/0  (conditional)
*
Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+
Tg(Col1a1-cre)1Kry/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory