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nitric oxide synthase 2, inducible
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
abnormal osteoclast differentiation
increased T cell proliferation
decreased susceptibility to induced colitis
pancreas inflammation
abnormal eosinophil cell number
decreased eosinophil cell number
increased single-positive T cell number
decreased osteoclast cell number
abnormal osteoclast morphology
increased IgG2a level
abnormal T-helper 1 physiology
abnormal macrophage physiology
abnormal osteoclast physiology
abnormal immune system morphology
enlarged inguinal lymph nodes
abnormal immune system physiology
abnormal adaptive immunity
increased interferon-gamma secretion
increased susceptibility to experimental autoimmune encephalomyelitis
abnormal inflammatory response
decreased susceptibility to endotoxin shock
decreased inflammatory response
increased inflammatory response
skin inflammation
abnormal response to infection
increased susceptibility to bacterial infection
increased susceptibility to parasitic infection
increased length of allograft survival
Availability Mouse Genotype
Nos2tm1Lau/Nos2tm1Lau *
Nos2tm1Liew/Nos2tm1Liew *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory