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Symbol
Name
ID
Nos1
nitric oxide synthase 1, neuronal
MGI:97360
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Elevated circulating hepatic transaminase concentration
Elevated sweat chloride
Dehydration
Hypercalciuria
Disease(s) Associated with NOS1
cystic fibrosis

Mouse Phenotypes
homeostasis/metabolism phenotype
abnormal response of heart to induced stress
abnormal vascular wound healing
decreased susceptibility to neuronal excitotoxicity
decreased circulating follicle stimulating hormone level
increased circulating luteinizing hormone level
increased circulating triglyceride level
abnormal renal water reabsorption
abnormal carbon dioxide production
abnormal oxygen consumption
increased oxygen consumption
insulin resistance
decreased adiponectin level
abnormal serotonin level
increased urine bicarbonate level
metabolic acidosis
increased urine pH
abnormal physiological response to xenobiotic
increased physiological sensitivity to xenobiotic
slow Wallerian degeneration
decreased susceptibility to ischemic brain injury
decreased cerebral infarct size
decreased susceptibility to injury
Availability Mouse Genotype
Nos1tm1Plh/Nos1tm1Plh *
Nos1tm2Plh/Nos1tm2Plh
Nos1tm1Plh/Nos1+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory