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v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Vocal cord paralysis
Intellectual disability
Specific learning disability
Disease(s) Associated with MYCN
Feingold syndrome

Mouse Phenotypes
nervous system phenotype
abnormal neuron differentiation
premature neuronal precursor differentiation
abnormal neuronal precursor proliferation
abnormal neural tube morphology
abnormal embryonic neuroepithelium morphology
abnormal embryonic neuroepithelial layer differentiation
decreased embryonic neuroepithelium thickness
abnormal brain morphology
abnormal forebrain development
abnormal cortical ventricular zone morphology
abnormal cerebellum development
abnormal cerebellar foliation
abnormal cerebellum external granule cell layer morphology
decreased brain size
abnormal medulla oblongata morphology
abnormal cerebral cortex morphology
telencephalon hypoplasia
abnormal cerebellum morphology
abnormal cerebellar Purkinje cell layer
decreased Purkinje cell number
ectopic Purkinje cell
abnormal cerebellar granule layer morphology
abnormal cerebellar molecular layer
small cerebellum
decreased neuronal precursor cell number
abnormal cranial ganglia morphology
small trigeminal ganglion
disorganized dorsal root ganglion
small dorsal root ganglion
dorsal root ganglion hypoplasia
Availability Mouse Genotype
Mycntm1Knd/Mycntm1Knd *
Mycntm1Jrt/Mycntm1Par *
Tg(Nes-cre)1Kln/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory