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Symbol Name ID |
Nkx2-5
NK2 homeobox 5 MGI:97350 |
| Darker colors indicate more annotations |
| Human Phenotypes | Macroglossia |
Muscular hypotonia |
| Disease(s) Associated with NKX2-5 | ||
| congenital nongoitrous hypothyroidism 5 |
| Mouse Phenotypes | abnormal impulse conducting system morphology |
abnormal Purkinje fiber morphology |
abnormal atrioventricular bundle morphology |
abnormal atrioventricular node morphology |
atrioventricular node hypoplasia |
abnormal myocardium layer morphology |
abnormal myocardial fiber morphology |
abnormal myocardial trabeculae morphology |
absent trabeculae carneae |
absent myocardial trabeculae |
disorganized myocardium |
dilated cardiomyopathy |
decreased ventricle muscle contractility |
abnormal myogenesis |
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| Availability | Mouse Genotype | ||||||||||||||
| Nkx2-5tm1Siz/Nkx2-5tm1Siz | |||||||||||||||
| Nkx2-5tm1Wehi/Nkx2-5tm1Wehi | |||||||||||||||
| Nkx2-5tm2Siz/Nkx2-5tm2Siz | |||||||||||||||
| Nkx2-5tm4Rph/Nkx2-5tm4Rph | |||||||||||||||
| Nkx2-5tm1Siz/Nkx2-5+ | |||||||||||||||
| Nkx2-5tm2.1Mwc/Nkx2-5+ | |||||||||||||||
| Nkx2-5tm2Siz/Nkx2-5+ | |||||||||||||||
| Nkx2-5tm3.1Mwc/Nkx2-5+ | |||||||||||||||
| Nkx2-5tm4Rph/Nkx2-5+ | |||||||||||||||
| Myl2tm1(cre)Krc/Myl2+ Nkx2-5tm1Krc/Nkx2-5tm1Krc (conditional) |
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| Nkx2-5tm1Krc/Nkx2-5tm1Krc Isl1tm1(cre)Tmj/Isl1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 02/12/2019 MGI 6.13 |
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