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Symbol
Name
ID

Nkx2-5
NK2 homeobox 5
MGI:97350

Phenotype annotations related to cellular

Darker colors indicate more annotations

Human Phenotypes	Abnormality of chromosome segregation
Disease(s) Associated with NKX2-5	Abnormality of chromosome segregation
hypoplastic left heart syndrome

Mouse Phenotypes		cardiac interstitial fibrosis	increased apoptosis	decreased cell proliferation
Availability	Mouse Genotype	cardiac interstitial fibrosis	increased apoptosis	decreased cell proliferation
	Nkx2-5^tm1Siz/Nkx2-5^tm1Siz
	Nkx2-5^tm1.1Gum/Nkx2-5^tm1.1Gum Tg(CAG-cre/Esr1*)5Amc/0 (conditional)
	Myl2^tm1(cre)Krc/Myl2⁺ Nkx2-5^tm1Krc/Nkx2-5^tm1Krc (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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