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Symbol
Name
ID
Nhlh2
nescient helix loop helix 2
MGI:97324
Phenotype annotations related to growth/size/body
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Delayed puberty
Abnormality of body height
Eunuchoid habitus
Disease(s) Associated with NHLH2
hypogonadotropic hypogonadism

Mouse Phenotypes
growth/size/body region phenotype
decreased lean body mass
increased body weight
obese
increased susceptibility to age related obesity
increased spleen weight
Availability Mouse Genotype
Nhlh2em1(IMPC)Mbp/Nhlh2em1(IMPC)Mbp
Nhlh2tm1b(KOMP)Mbp/Nhlh2tm1b(KOMP)Mbp
Nhlh2tm1Irk/Nhlh2tm1Irk
Nhlh2tm1Thbr/Nhlh2tm1Thbr
Nhlh2tm1Irk/Nhlh2+
Nhlh2tm2Thbr/Nhlh2tm2Thbr
Tg(Pomc-EGFP)1Low/0
Tg(Pomc1-cre)16Lowl/0  (conditional)
*
Nhlh2tm2Thbr/Nhlh2tm2Thbr
Tg(Agrp-cre)1Gsb/0  (conditional)
*
Kiss1tm1.1(cre)Uboe/Kiss1+
Nhlh2tm2Thbr/Nhlh2tm2Thbr  (conditional)
*
Nhlh2tm2Thbr/Nhlh2tm2Thbr
Tg(CMV-cre)1Cgn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory