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Symbol
Name
ID
Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
MGI:97312
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations

Mouse Phenotypes
decreased B cell proliferation
increased B cell proliferation
decreased T cell proliferation
abnormal class switch recombination
myeloid hyperplasia
extramedullary hematopoiesis
abnormal bone marrow cell morphology/development
decreased erythrocyte cell number
decreased mean corpuscular hemoglobin concentration
decreased myeloid dendritic cell number
decreased B-1 B cell number
decreased B-1a cell number
decreased marginal zone B cell number
decreased NK cell number
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number
decreased central memory CD4-positive, alpha-beta T cell number
decreased effector memory CD4-positive, alpha-beta T cell number
increased CD4-positive, alpha beta T cell number
increased central memory CD8 positive, alpha-beta T cell number
decreased CD8-positive, naive alpha-beta T cell number
decreased NK T cell number
decreased memory T cell number
decreased regulatory T cell number
decreased single-positive T cell number
increased T cell number
decreased osteoclast cell number
increased leukocyte cell number
enlarged spleen
abnormal lymphocyte physiology
abnormal B cell physiology
decreased IgA level
decreased IgE level
increased IgE level
decreased IgG1 level
increased IgG1 level
decreased IgG3 level
decreased IgG level
decreased IgM level
decreased immunoglobulin level
increased immunoglobulin level
abnormal CD4-positive, alpha-beta T cell physiology
abnormal macrophage physiology
Availability Mouse Genotype
Nfkb1M1Btlr/Nfkb1M1Btlr
Nfkb1m2Btlr/Nfkb1m2Btlr
Nfkb1M3Btlr/Nfkb1M3Btlr
Nfkb1M4Btlr/Nfkb1M4Btlr
Nfkb1M5Btlr/Nfkb1M5Btlr
Nfkb1M6Btlr/Nfkb1M6Btlr
Nfkb1tm1a(KOMP)Wtsi/Nfkb1tm1a(KOMP)Wtsi
Nfkb1tm1Bal/Nfkb1tm1Bal
Nfkb1tm1Brv/Nfkb1tm1Brv
Nfkb1tm1Sley/Nfkb1tm1Sley
Nfkb1M1Btlr/Nfkb1+
Nfkb1m2Btlr/Nfkb1+
Nfkb1M3Btlr/Nfkb1+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory