Symbol Name ID |
Nf1
neurofibromin 1 MGI:97306 |
Darker colors indicate more annotations |
Human Phenotypes | Lower limb muscle weakness |
Muscle weakness |
Abdominal wall muscle weakness |
Rhabdomyosarcoma |
Disease(s) Associated with NF1 | ||||
neurofibromatosis 1 | ||||
neurofibromatosis-Noonan syndrome | ||||
spinal neurofibromatosis |
Mouse Phenotypes | abnormal myocardium layer morphology |
thin myocardium compact layer |
disorganized myocardium |
thin myocardium |
abnormal myoblast differentiation |
increased myoblast proliferation |
abnormal muscle morphology |
abnormal muscle development |
abnormal myogenesis |
delayed muscle development |
abnormal muscle fiber morphology |
decreased skeletal muscle fiber number |
decreased muscle weight |
skeletal muscle hypoplasia |
decreased skeletal muscle mass |
skeletal muscle fibrosis |
abnormal muscle physiology |
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Availability | Mouse Genotype | |||||||||||||||||
Nf1tm1Fcr/Nf1tm1Fcr | ||||||||||||||||||
Nf1tm1Tyj/Nf1tm1Tyj | ||||||||||||||||||
Nf1tm1Tyj/Nf1tm2Tyj | ||||||||||||||||||
Nf1tm1Par/Nf1tm1Par Tg(Tek-cre)1Ywa/0 (conditional) |
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Nf1tm1Par/Nf1tm1Par Tg(Prrx1-cre)1Cjt/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/19/2024 MGI 6.23 |
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