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Symbol
Name
ID
Myb
myeloblastosis oncogene
MGI:97249
Phenotype annotations related to hematopoietic system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
hematopoietic system phenotype
abnormal megakaryocyte differentiation
decreased T cell proliferation
abnormal embryonic erythropoiesis
small thymus
thymus hypoplasia
decreased thymocyte number
abnormal definitive hematopoiesis
decreased common myeloid progenitor cell number
absent common myeloid progenitor cells
abnormal erythropoiesis
abnormal B cell differentiation
arrested B cell differentiation
abnormal T cell differentiation
abnormal double-negative T cell morphology
decreased double-negative T cell number
increased double-negative T cell number
decreased double-positive T cell number
arrested T cell differentiation
anemia
increased bone marrow cell number
abnormal megakaryocyte morphology
increased megakaryocyte cell number
abnormal common lymphocyte progenitor cell morphology
decreased erythroid progenitor cell number
abnormal myeloblast morphology/development
decreased eosinophil cell number
abnormal erythrocyte morphology
decreased erythrocyte cell number
decreased hematocrit
increased nucleated erythrocyte cell number
increased number of Howell-Jolly bodies
macrocytosis
polychromatophilia
decreased neutrophil cell number
thrombocytosis
abnormal platelet shape
decreased mature B cell number
decreased B-1 B cell number
decreased B cell number
decreased pre-B cell number
decreased CD4-positive, alpha beta T cell number
decreased CD8-positive, alpha-beta T cell number
increased CD8-positive, alpha-beta T cell number
decreased gamma-delta T cell number
decreased T cell number
decreased single-positive T cell number
reticulocytosis
decreased hematopoietic stem cell number
increased hematopoietic stem cell number
abnormal hematopoietic stem cell morphology
abnormal leukocyte morphology
abnormal single-positive T cell number
abnormal spleen morphology
increased spleen red pulp amount
enlarged spleen
small spleen
decreased spleen white pulp amount
Availability Mouse Genotype
Mybboo/Mybboo
MybM303V/MybM303V
Mybtm1.1Cgn/Mybtm1.1Cgn
Mybtm1Jof/Mybtm1Jof
Mybtm1Ssp/Mybtm1Ssp
Mybtm2.2Epr/Mybtm2.2Epr *
Tg(CD2-Myb/en)2Kmw/Tg(CD2-Myb/en)2Kmw
Mybtm1.1Cgn/Myb+
Mybtm1Jof/Mybtm1Ssp
Tg(CD2-Myb/en)2Kmw/?
Mybtm1Cgn/Mybtm1Cgn
Tg(Lck-cre)548Jxm/0  (conditional)
Mybtm1Cgn/Mybtm1Cgn
Tg(Lck-cre)1Cwi/0  (conditional)
Mybtm1Epr/Mybtm1Epr
Tg(Lck-cre)548Jxm/0  (conditional)
Mybtm1Epr/Mybtm1Epr
Tg(Cd4-cre)1Cwi/0  (conditional)
Mybtm1Cgn/Mybtm1.1Cgn
Tg(Lck-cre)548Jxm/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory