|
Symbol Name ID |
Msx2
msh homeobox 2 MGI:97169 |
| Darker colors indicate more annotations |
| Human Phenotypes | Frontal bossing |
Prominent occiput |
Parietal foramina |
Biparietal narrowing |
Brachycephaly |
Brachyturricephaly |
Craniosynostosis |
Coronal craniosynostosis |
Bicoronal synostosis |
Unicoronal synostosis |
Left unicoronal synostosis |
Right unicoronal synostosis |
Lambdoidal craniosynostosis |
Pansynostosis |
Sagittal craniosynostosis |
Dolichocephaly |
Scaphocephaly |
Trigonocephaly |
Turricephaly |
Oxycephaly |
Micrognathia |
Retrognathia |
Hypoplasia of the maxilla |
Malar flattening |
Shallow orbits |
Abnormal posterior cranial fossa morphology |
Microcephaly |
Macrocephaly |
Metopic synostosis |
Wormian bones |
Wide anterior fontanel |
Encephalocele |
Occipital encephalocele |
Congenital craniofacial dysostosis |
Genu valgum |
Shortening of all distal phalanges of the fingers |
Cone-shaped epiphyses of the phalanges of the hand |
Shortening of all middle phalanges of the fingers |
Broad thumb |
Triphalangeal thumb |
Arachnodactyly |
Hallux valgus |
Cone-shaped epiphyses of the toes |
Brachydactyly |
Metatarsus adductus |
Metaphyseal widening |
Dislocated radial head |
Genu recurvatum |
Carpal bone malsegmentation |
Joint contracture of the hand |
Camptodactyly |
Joint hypermobility |
Short clavicles |
Lateral clavicle hook |
Supernumerary ribs |
Thin ribs |
Pectus carinatum |
Pectus excavatum |
Scoliosis |
C1-C2 vertebral abnormality |
Osteopenia |
Multiple exostoses |
| Disease(s) Associated with MSX2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| craniosynostosis | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| parietal foramina |
| Mouse Phenotypes | abnormal neurocranium morphology |
abnormal frontal bone morphology |
frontal bone foramen |
small interparietal bone |
small supraoccipital bone |
degenerate molars |
ameloblast degeneration |
abnormal enamel organ morphology |
abnormal stellate reticulum morphology |
abnormal stratum intermedium morphology |
brittle teeth |
malocclusion |
decreased osteoclast cell number |
short femur |
short tibia |
abnormal appendicular skeleton morphology |
abnormal long bone hypertrophic chondrocyte zone |
abnormal axial skeleton morphology |
decreased bone mineral density |
decreased compact bone thickness |
abnormal trabecular bone morphology |
decreased chondrocyte number |
abnormal skeleton development |
chondrodystrophy |
abnormal bone ossification |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||
| Msx2tm1.1Yvla/Msx2tm1.1Yvla | ||||||||||||||||||||||||||
| Msx2tm1Rilm/Msx2tm1Rilm | ||||||||||||||||||||||||||
| Msx2tm1Rilm/Msx2+ | ||||||||||||||||||||||||||
| Msx2tm1Rem/Msx2tm1Rem Tg(Msx2-cre)5Rem/0 (conditional) |
||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/09/2024 MGI 6.23 |
|
|
|
||
Analysis Tools