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Symbol
Name
ID
Mmp2
matrix metallopeptidase 2
MGI:97009
Phenotype annotations related to vision/eye
Darker colors indicate more annotations
Human Phenotypes
Retinal hemorrhage
Retinal arteritis
Presenile cataracts
Choroidal neovascularization
Optic atrophy
Optic disc drusen
Macular degeneration
Angioid streaks of the fundus
Retinal detachment
Retinal peau d'orange
Retinal hole
Retinopathy
Blue sclerae
Increased axial length of the globe
Nystagmus
Ophthalmoparesis
Myopia
High myopia
Diplopia
Amaurosis fugax
Metamorphopsia
Visual impairment
Reduced visual acuity
Blindness
Visual field defect
Visual loss
Ptosis
Disease(s) Associated with MMP2
myopia
pseudoxanthoma elasticum
temporal arteritis

Mouse Phenotypes
abnormal induced retina neovascularization
cataract
increased inner canthal distance
abnormal vitreous body morphology
Availability Mouse Genotype
Mmp2em1(IMPC)Mbp/Mmp2em1(IMPC)Mbp
Mmp2tm1Ito/Mmp2tm1Ito

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory