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Symbol
Name
ID
Lpl
lipoprotein lipase
MGI:96820
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Increased circulating chylomicron concentration
Increased LDL cholesterol concentration
Increased VLDL cholesterol concentration
Hypercholesterolemia
Hyperlipidemia
Lactescent serum
Elevated apolipoprotein A-II level
Elevated apolipoprotein B level
Disease(s) Associated with LPL
familial combined hyperlipidemia
familial lipoprotein lipase deficiency

Mouse Phenotypes
decreased circulating HDL cholesterol level
increased circulating HDL cholesterol level
decreased circulating LDL cholesterol level
increased circulating VLDL cholesterol level
increased circulating cholesterol level
increased circulating phospholipid level
increased circulating triglyceride level
increased circulating VLDL triglyceride level
hyperlipidemia
cyanosis
abnormal glucose homeostasis
abnormal lipid homeostasis
increased cholesterol level
abnormal lipid level
abnormal fatty acid level
increased triglyceride level
Availability Mouse Genotype
Lpltm1Bres/Lpltm1Bres
Lpltm1Sem/Lpltm1Sem
Lpltm1Bres/Lpl+
Lpltm1Sem/Lpl+
Lpltm1Ijg/Lpltm1Ijg
Tg(Myh6-cre)2182Mds/?  (conditional)
Lpltm1Ijg/Lpltm1Ijg
Tg(Myh6-cre)2182Mds/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory